https://www.stephenriffle.com/freelance-work daily 0.75 2023-01-16 https://www.stephenriffle.com/most-viewed daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556752487782-C10DLWHEVR3Q7G6C5ICN/astro2.jpg Most viewed https://www.stephenriffle.com/most-viewed/category/Genetics monthly 0.5 https://www.stephenriffle.com/biographies daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556728389187-L9ZAIIK362FI3R6OY22R/dr_gobind_khorana.png Biographies https://www.stephenriffle.com/undergraduate-work daily 0.75 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556902843318-O2YH78YYXVRKKQY8DE69/bi-2015-007459_0005.gif Work with Dr. Les Wilson https://www.stephenriffle.com/undergraduate-work/bii-tubulin monthly 0.5 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556900257905-JF2UWE0YCHSVBLB17VKL/bi-2015-007459_0005.gif Work with Dr. Les Wilson - Effects of Eribulin on Microtubule Binding and Dynamic Instability Are Strengthened in the Absence of the βIII Tubulin Isotype Possible model for eribulin binding to microtubule plus ends in the presence or absence of βIII tubulin. (A). Eribulin (Erb) bound to the plus tip of a microtubule is shown as a red circle, unbound eribulin is shown as a black circle. Potential eribulin binding site between tubulin dimers (dashed circle) is sterically blocked by the rigid conformation induced by βIII tubulin. βx denotes any β tubulin isotype other than βIII (βI, βIII, βIV). (B). In the absence of βIII tubulin, the microtubule end is less rigid due to βx isotypes allowing for greater flexibility at the plus tip. Eribulin is able to bind both its terminal binding sites and to internal sites between tubulin dimers, increasing the maximum stoichiometry. When bound to an interdimer site, eribulin strengthens longitudinal tubulin-tubulln interactions (red arrows), stabilizing the plus end by suppressing rate and extent of shortening and the catastrophe frequency. https://www.stephenriffle.com/undergraduate-work/taccaaj monthly 0.5 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556900045976-JS12WKKR8D5R0Z3STQKS/1476-4598-13-41-1.jpg Work with Dr. Les Wilson - The taccalonolides and paclitaxel cause distinct effects on microtubule dynamics and aster formation Mitotic asters induced by paclitaxel or the taccalonolides. The mitotic asters in HeLa cells treated with vehicle, 12 nM paclitaxel, 5 μM taccalonolide A or 20 nM taccalonolide AJ, the minimum concentrations that caused maximum mitotic accumulation, were visualized by indirect immunofluorescence for β-tubulin (top). DNA was visualized by DAPI staining (middle) and merged images are shown with microtubules in green and DNA in blue (bottom). https://www.stephenriffle.com/health daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556728566203-RMOIP7L2EXIGSACRZTQU/BRCA-ACMG_b.png Health https://www.stephenriffle.com/freelance-work-mrs daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1605632547839-58PGGKMIL92X3M5NKV9Z/3D-nano-DNA-no-1.png Material Research Society https://www.stephenriffle.com/phd-work daily 0.75 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556902807796-Z6F6UNJBH43RZ9OUKNO1/uh.jpg PhD work https://www.stephenriffle.com/phd-work/retinopathy monthly 0.5 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556901940070-EZG7SOMJ3R3ABTTDLWSY/Retina%2Bvasculature.jpg PhD work - The Protein Tyrosine Phosphatase Activity of Eyes Absent Contributes to Tumor Angiogenesis and Tumor Growth. Unpublished image of pathological overgrowth of mouse retinal vasculature (photo-credit Yoshinobu Odaka, circa 2017) https://www.stephenriffle.com/phd-work/3d-spheroid-review monthly 0.5 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556901021253-54D0USIRHFEVFSALTVCT/13046_2017_570_Fig1_HTML.jpg PhD work - Modeling tumor cell adaptations to hypoxia in multicellular tumor spheroids https://www.stephenriffle.com/phd-work/linking-hypoxia-proliferation-dna-damage monthly 0.5 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556901351781-S8B2DPSDPAHU6P4HSMJB/uh.jpg PhD work - Linking hypoxia, DNA damage and proliferation in multicellular tumor spheroids Cross section of an immunostained tumor spheroid. Cell nuclei are labelled with DAPI (Blue). Proliferating cells are labelled in green and cells with DNA damage, as marked by y-H2AX, are labelled in red. The dotted line indicates the hypoxic zone. https://www.stephenriffle.com/helix-research daily 0.75 2021-10-17 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556902748809-8DFUP6TKZRKMX5SY4ZDO/Screen+Shot+2019-05-01+at+6.07.22+PM.png Academic work with Helix https://www.stephenriffle.com/helix-research/covid-19-research-survey monthly 0.5 2021-10-17 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1634510385514-3FLON4I4PWZSOL2SGIVO/Blog-Email_GWAS_Severe_COVID19_Chrom3.png Academic work with Helix - COVID-19 Research Survey - Make it stand out Graphic created to demonstrate hits from a GWAS performed using Helix research survey data. https://www.stephenriffle.com/helix-research/sars-cov-2-interaction-domain monthly 0.5 2021-10-17 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1587762078740-D742EN9XU5BVWLVKB4ML/ACE2-res400-lead.png Academic work with Helix - Revealing variants in SARS-CoV-2 interaction domain of ACE2 and loss of function intolerance through analysis of >200,000 exomes - ACE2 protein ribbon structure ACE2 ribbon structure; Photo credit: EMW on Wikimedia Commons https://www.stephenriffle.com/helix-research/gc-2030 monthly 0.5 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556902276875-TLQU81NFOD74LUP2WTLT/Screen+Shot+2019-05-01+at+6.07.22+PM.png Academic work with Helix - Genetic counseling, 2030: An on-demand service tailored to the needs of a price conscious, genetically literate, and busy world. Sub panel discussing data privacy. Full panel can be found in the supplemental materials section. https://www.stephenriffle.com/helix daily 0.75 2015-08-25 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556723280726-4RTEC1MVGGIXHL34C565/Bianca-Steve_b.png Articles written for Helix https://www.stephenriffle.com/helix-ancestry daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556727506790-UEDNZLE0DVTT7M8NKA0R/neanderthal2.jpg Ancestry, evolution, and more https://www.stephenriffle.com/for-professional-audience daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1605707144966-PDIGHSZIUU3HWP1MIC6J/TY-video-Hero-artist-3.png Other projects at Helix https://www.stephenriffle.com/pendulum-therapeutics daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1605713374842-EAUYAHYBXFE2FRKCJ321/Pendulum_Blog_Akkermansia_muciniphila_T2D_930x325_2X_b395bde7-a376-4988-8474-0fa783a49ff9.jpg Pendulum Therapeutics https://www.stephenriffle.com/twist-bioscience daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1634506660868-85BC8GNCCUP59DJUTGJ2/Screen+Shot+2021-09-19+at+3.34.17+PM.png Twist Bioscience https://www.stephenriffle.com/nature-branded-content daily 0.75 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1634506511756-09W7DBW10N90GDAMEFEG/NRCM-BC-Ki-67.jpeg Nature Branded Content https://www.stephenriffle.com/bedrock-ocean daily 0.75 2023-01-16 https://www.stephenriffle.com/wildlife-photography daily 0.75 2021-12-22 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1634512048176-FIIZLI3J85SFROSCZI8D/IMG_9015.JPG Wildlife of San Francisco 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out Whatever it is, the way you tell your story online can make all the difference. https://www.stephenriffle.com/science-writing/advancing-point-of-care-diagnostics-with-an-ancient-process monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/2f8e113c-c233-4616-beb6-548c6b56eccd/Potatoes-in-bowl.png Science Writing - Advancing point-of-care diagnostics with an ancient process - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.stephenriffle.com/science-writing/exome-20-launch monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/a560eaf5-c1be-4752-83c4-f3aace584bcb/Screen+Shot+2021-12-22+at+2.42.22+PM.png Science Writing - Detecting the Unexpected - Make it stand out Image repurposed from the original post on the Twist blog https://www.stephenriffle.com/science-writing/biosecurity-2021 monthly 0.5 2023-01-16 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Photo credit: Wikimedia Commons https://www.stephenriffle.com/science-writing/underwater-sound monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1634507516095-NM9MQF5RI5A9INPX59V7/pexels-daniel-torobekov-5319953.jpg Science Writing - Sound beneath the waves - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.stephenriffle.com/science-writing/multiplex-testing-helps-provide-critical-insights-as-respiratory-viruses-surge monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1634506864660-5T27EG7TYI8I6U6KNBIN/NRCM-Flu_COVID.jpeg Science Writing - Multiplex testing helps provide critical insights as respiratory viruses surge - Make it stand out Respiratory viruses, including SARS-CoV-2, can present similar symptoms but vary widely in the treatments they require. 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In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/zombie-dna monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556753004827-UTBC97JO16KXPFH9235D/Elephant_2.jpg Science Writing - Do humans have zombie DNA? https://www.stephenriffle.com/science-writing/jcwright monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556924462785-HW3E80PDWQ4WWKFL50NG/JCWright2_b.png Science Writing - Dr. Jane C. Wright: Finding breakthroughs in cancer research Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/rosalind-franklin monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556925573761-QE63NPLM2J553C0FJN82/Rosalind-franklin-Dday_b.png Science Writing - Dr. Rosalind Franklin: DNA legend Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/martha-chase monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556925368490-DB7Q85G8PLFXK3KNRN76/women-in-science_03_marthachase.png Science Writing - Dr. Martha Chase: A defining moment in genetics has her name on it Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/nettie-stevens monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556925200539-2VY6NI7910YRH96JEP8V/women-in-science_04_nettiestevens.png Science Writing - Dr. Nettie Stevens: Making genetics history with mealworms Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/barb-mcclintock monthly 0.5 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556925698473-LQRRG5Z31T95OOSWYKLO/women-in-science_01_barbaramcclintock.png Science Writing - Dr. Barbara McClintock: Maize, jumping genes, and a Nobel Prize Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/mary-lyon monthly 0.5 2019-05-03 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556924897938-WKLDL38GBH7SOZZKSFY6/women-in-science_05_marylyon.png Science Writing - Dr. Mary Lyon: From mice to mosaicism Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/mummy-heart-disease monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556751993429-XLGNF0ACTLXQ7M2254VG/mummy-up-front_b.png Science Writing - What can an ice mummy teach us about heart disease? https://www.stephenriffle.com/science-writing/ernest-everett-just monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556924701587-NOS2BLOCQWO0X08KGSZW/EEJust2_b.png Science Writing - Dr. Ernest Everett Just: Using sand dollars to solve biological mysteries Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/mmdaly monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556924287676-6DLVG5EO0D6B71M7H8XH/MMDaly_b.png Science Writing - Dr. Marie Maynard Daly: A love for the heart Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/bowman monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556921630531-XMSYXQ421ZTZQDDY1KKO/JEBowman_b.png Science Writing - Dr. James E. Bowman: Expert pathologist and champion for medical ethics Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/hbranson monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556921441081-O3RKMONPHYB45DYRMJ3Q/HBranson_b.png Science Writing - Dr. Herman Branson: A pioneer in protein structures Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/hgkhorana monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556921196859-FPY7GDZ5R2H9X5P3CJ1Y/dr_gobind_khorana+%281%29.png Science Writing - Dr. Har Gobind Khorana: A trailblazing code breaker Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/ccli monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556920994458-5L3O3W5PONRNKMC9R7GX/ChingChunLi.png Science Writing - Dr. Ching Chun Li: Guarding the heart of science Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/ohno monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556920801141-I661MFS5YOFIRJOF3U2M/SusumuOhnoFB_b.png Science Writing - Dr. Susumu Ohno: Finding the beauty in DNA Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/jhtijio monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556920620021-S18DZMCYSWB0UX8VVCWM/JoeHinTjio_b.png Science Writing - Dr. Joe Hin Tjio: The science of counting Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/ll-sforza monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556920453116-C0R6K7CCX1XWHXXDRBRB/Bio_b.png Science Writing - Remembering Dr. Luigi Luca Cavalli-Sforza, a pioneer in population genetics Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/bhm-chinn monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556920259231-DB3EM7R7N2SMGLK9DQ1R/BHM-19-Chinn.png Science Writing - Treating Harlem: Dr. May Edward Chinn Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/bhm-reddick monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556919828351-0HC7JB05VXUO56TJOTGH/BHM-19-Reddick.png Science Writing - Tracing human development with chickens: Mary Logan Reddick Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/bhm-edwards monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556919586720-MFTBVNJLO6QUEZ3JHB41/BHM-19-Edwards_2.png Science Writing - Feeding a nation: Dr. Cecile Hoover Edwards Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/bhm-percy-julian monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556919252774-XMBCDH24JR9LC7HDUWF9/BHM-19-Julian.png Science Writing - Challenging the status quo: Who was Percy Julian? Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/bristlecone-pine monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556726313898-L0S9Q120EU5WT98LP8CG/bristlecone-pine_b.png Science Writing - How much of the world has your DNA seen? https://www.stephenriffle.com/science-writing/facets-of-the-world monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556725111822-IJVWSFGG7L6P147XLBLE/AncestryBlog_LeadImage.jpg Science Writing - Facets of the world https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556725022285-0EKSYJ6L7X6BBXZRM7OP/Prism-Image.jpg Science Writing - Facets of the world https://www.stephenriffle.com/science-writing/african-archaic-ancestry monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556757127584-AAEB91KNGS7XOZOQ59M5/african_archaic_admixture_b.jpg Science Writing - The genetics of ancient Africa and a mysterious human population Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/mars-founder-effect monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556756762219-TPIVNSTICVHF69QGSYU2/Mars-Rover_b.jpg Science Writing - Colonizing Mars is hard—and genetics is one reason why Photo credit: NASA Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556757080404-O3I1YIDSWD8VHYXQRQC5/Founder-effect_b.jpg Science Writing - Colonizing Mars is hard—and genetics is one reason why https://www.stephenriffle.com/science-writing/de-extinction monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556756422798-LVXEGG2X3SFLHPHJR22D/mammoth_b.png Science Writing - Will the woolly mammoth walk again? Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/linkage-disequilibrium monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556756190037-OS8CU2UF59RSHYRWGQVT/Nuk-luk-ld_2-2_b.png Science Writing - Scientists have found a time machine—it’s your DNA https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556756330876-N65E2P3S70ZEWPTJ3SEE/recombination_gif_b.gif Science Writing - Scientists have found a time machine—it’s your DNA Here, recombination is demonstrated. Recombination like this occurs before your DNA can be passed to the next generation. Three segments of DNA from one parent (shown as yellow, green and black lines) align next to three segments from the other parent. DNA is then swapped between segments in random locations to produce hybrid DNA sequences. https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556756216699-CDQQDOC9N31IAEQTUM8X/Nuk-luk-ld_1_b.png Science Writing - Scientists have found a time machine—it’s your DNA https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556756018028-F9LUNV93JWC67AGKT0XV/ld-dna101_b.jpg Science Writing - Scientists have found a time machine—it’s your DNA Note: This blog was originally published on the Helix Blog. At the moment, my html chops are only so-so. In order to see this blog in its full glory, I strongly recommend navigating to its original home here. https://www.stephenriffle.com/science-writing/natural-selection-moths monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556755738752-GEVJHINJZME8Q11RY9CV/Natural_Selection_b.png Science Writing - Evolution is happening before our very eyes—just ask the peppered moths https://www.stephenriffle.com/science-writing/corgi-neanderthal monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556755474778-E8QVBANAMULWF0O36T84/corgi_1_b.png Science Writing - What can corgis teach us about Neanderthals? https://www.stephenriffle.com/science-writing/penetrance-expressivity monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556755262112-TMAEAHXFQ5Y8XSELCGTU/eyes_b.jpg Science Writing - Understanding genetics: What are “penetrance” and “expressivity”? https://www.stephenriffle.com/science-writing/neandertal-1 monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556754615529-HO3G1560NRZALMRN2WFO/neanderthal2.jpg Science Writing - Our Neanderthal DNA: Who were Neanderthals and Denisovans? https://www.stephenriffle.com/science-writing/duck-moles monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556754198346-V40OMV1B430ZX9259UXM/dreamy-platypus_b.png Science Writing - Does a platypus dream at night? https://www.stephenriffle.com/science-writing/space-radiation monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556753829519-AKAM3VEL4O0PCLGP3BHC/astro1_b.jpg Science Writing - Can humans evolve to make space travel safer? https://www.stephenriffle.com/science-writing/sibling-ancestry monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556753669050-VRHX5GZTGR2AJR2VNPGM/sibling-ancestry-fig-2_b.jpg Science Writing - You could have different ancestry than your biological siblings. How? Figure 2. In this diagram, solid colors represent chromosomes from one of the respective grandparents. Circles indicate females, and squares indicate males. https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556753511291-1AP6FYW80RLQ2V7SF6F7/siblings-2_b.jpg Science Writing - You could have different ancestry than your biological siblings. How? https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556753641518-C4WPAWZ5QGLP6PF6AON6/sib+ancestry+gif.gif Science Writing - You could have different ancestry than your biological siblings. How? Figure 1. https://www.stephenriffle.com/science-writing/neandertal-list monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556752653887-DKHTR049S85JWE9PXI6C/neanderthal-1.jpg Science Writing - 3 amazing things you didn’t know about ancient humans https://www.stephenriffle.com/science-writing/whatsnext monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556726845234-OUPIQ4C9ZIZ9UMMO7SXR/Ancestry-blog-lead.jpg Science Writing - So, you’ve discovered where your ancestors lived. What’s next? https://www.stephenriffle.com/science-writing/fruit-fly monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556725603221-X06HY1IXSVAZ67E82S5A/drosophila_b.png Science Writing - The genetic bonds we share with a tiny, annoying bug https://www.stephenriffle.com/science-writing/bioinspired-kidney-scaffold monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556899216844-6U7B2BBT80YM87V1ERVV/bioinspired-scaffold.jpg Science Writing - Bioinspired hybrid polymer scaffold regenerates and repairs mouse kidney Schematic representation of a bioinspired scaffold that neutralizes the acidic microenvironment through the Mg(OH)2 to inhibit the inflammatory response. Compared to PLGA only, this bioinspired scaffold shows good cytocompatibility by the decellularized extracellular matrix on a surface of the scaffold. Credit: ACS Central Science https://www.stephenriffle.com/science-writing/spider-dragline-silk monthly 0.5 2023-01-16 https://images.squarespace-cdn.com/content/v1/5cc8b4b380f4be00012fcca1/1556898285417-HUKIEAWCOXU3NU8H8PUV/Spider-Dragline-a-b.jpg Science Writing - Spider dragline silk acts as a rotational actuator (a) Torsional actuation of N. pilipes dragline silk (98 mm in length, 3.1 ± 0.1 μm in diameter) to relative humidity (RH) cyclically changing from ~40% to ~100%. The horizontal dashed lines show the RH thresholds for the triggering of twist. The vertical dashed lines show the start and end of the induced twist. (b) Hydrogen bonds shown in blue in spider silk proteins (i) MaSp1 and (ii) MaSp2 molecules. 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